10
Dec
What Gene Or Chromosome Is Mutated In Cystic Fibrosis. This mutated gene the cystic fibrosis transmembrane conductance regulator CFTR gene is located on the long arm q of chromosome 7 7q312. Mutations in the CFTR gene cause cystic fibrosis. Cells that contain the defective protein encoded by the gene produce unusually thick and sticky mucus that builds up in the lungs and other organs. People who have cystic fibrosis have a faulty protein that affects the bodys cells tissues and the glands that make mucus and sweat.
To have CF a baby must get two copies of the CF gene one from each parent. The exact combination of mutations your genotype and other factors will dictate how severe the condition is for you and which organs in the body are worst affected. Both parents who are carriers of the mutated gene each pass one mutated gene to the child. The CFTR gene provides instructions for making a protein called the cystic fibrosis transmembrane conductance regulator. Cells that contain the defective protein encoded by the gene produce unusually thick and sticky mucus that builds up in the lungs and other organs. The majority of people with cystic fibrosis will have the genetic mutation called Delta F508.
The CFTR gene provides instructions for making a channel that transports negatively charged particles called chloride ions into and out of cells.
Cystic fibrosis occurs when a child inherits a changed mutated gene from both parents. Which option below best describes what most likely happens for a child to develop this condition. Cystic fibrosis occurs when a child inherits a changed mutated gene from both parents. Cystic fibrosis transmembrane conductance regulator CFTR is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene. Both parents who are carriers of the mutated gene each pass one mutated gene to the child. This mutated gene the cystic fibrosis transmembrane conductance regulator CFTR gene is located on the long arm q of chromosome 7 7q312.