23
Aug
Lactic Acidosis After Seizure. To define the time course of the metabolic acidosis that follows a single grand-mal seizure we obtained serial blood samples from eight consecutive patients. A 39yearold man developed a single tonicclonic seizure lasting for 2 min as witnessed by an ambulance crew while being transferred to hospital following an overdose of codydramol. Lactic acidosis is a common cause of metabolic acidosis and is usually connected with high mortality. Seizure Lactic Acidosis Increased Blood Lactate Indicates Hypoxia Or Circulatory Failure.
Units of measurement will be mML. Lactic acidosis can occur due to. I excessive tissue lactate production ii impaired hepatic metabolism of lactate large capacity to clear clinically there is often a combination of the above to produce a persistent lactic acidosis CAUSES Cohen Woods classification Type A. It is a form of metabolic acidosis in which excessive acid accumulates due to a problem with the bodys oxidative metabolism. Baseline lactate serum level is expected to be less than 22. Lactic acidosis is a common cause of metabolic acidosis and is usually connected with high mortality.
This type of measurement may be useful in signalling the occurrence or recent history of a seizure.
Significantly elevated prolactin levels are often found up to an hour after the event with a peak after about 1525 min. The investigators will assess the intravenous lactic acid within 10 minutes after end of a seizure. Baseline lactate serum level is expected to be less than 22. Values will consist of lactic acid measurements in serum collected by IV immediately post-seizure. If lactic acid rises within a few minutes of a seizure than it might be feasible to develop lactic acid sensors to provide notification of a recent seizure. Lactic acidosis is a common cause of metabolic acidosis and is usually connected with high mortality.