Fructose And Insulin Resistance. In summary dietary fructose intake strongly promotes hepatic insulin resistance via complex interplay of several metabolic pathways at least some of which are independent of increased weight gain and caloric intake. Of particular interest to researchers is the link between high fructose diets and insulin resistance as diets high in fructose have been shown to induce weight gain and insulin resistance in experimental animals. Fructose-induced insulin resistant states are commonly characterized by a profound metabolic dyslipidemia which appears to result from hepatic and intestinal overproduction of atherogenic lipoprotein particles. Increased oxidative stress and inflammation in your.
We present possible mechanisms by which fructose causes insulin resistance and suggest actions based on this association that have therapeutic implications. The regular consumption of excess fructose can also make your body become resistant to the effects of insulin. Of particular interest to researchers is the link between high fructose diets and insulin resistance as diets high in fructose have been shown to induce weight gain and insulin resistance in experimental animals. Over time chronic overconsumption of sugar leads to high insulin levels. Excessive consumption of fructose or high fructose corn syrup can cause insulin resistance a condition that can lead to type 2 diabetes. Excess fructose consumption contributes to development obesity metabolic syndrome and nonalcoholic fatty liver disease NAFLD.
High fructose intake from added sugar not fruit has been linked to insulin resistance in both rats and humans 20 21 22.
Fructose does in fact have specific metabolic characteristics that could potentially contribute to a metabolic profile associated with increased body adiposity and the insulin resistance metabolic syndrome. The current evidence shows that the fructose but not glucose component of dietary sugar drives metabolic complications and contradicts the notion that fructose is merely a source of palatable calories that leads to increased weight gain and insulin resistance. Cause insulin resistance which can lead to obesity and type II diabetes. The regular consumption of excess fructose can also make your body become resistant to the effects of insulin. The sugar obtained from the digestion of fruits can elevate your blood sugar levels which in turn push your pancreas to produce insulin. Over time chronic overconsumption of sugar leads to high insulin levels.