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Erdheim Chester Pathology Outlines. Das Geschlechtsverhältnis männlichweiblich beträgt. Large foamy histiocytes containing lipid lymphocytic aggregates fibrosis Rare Touton-like giant cells Microscopic histologic images. Pathologists among the many other integral specialties have been an important role in the process of diagnosing Erdheim-Chester Disease. ErdheimChester disease ECD is a rare disease characterized by the abnormal multiplication of a specific type of white blood cells called histiocytes or tissue macrophages technically this disease is termed a non- Langerhans-cell histiocytosis.
Das mittlere Alter bei Erkrankungsbeginn liegt bei 53 Jahren. Kovacsksmhtorontoonca Pituitary morphologic changes in patients with Erdheim-Chester disease have not been described in detail. Erdheim-Chester disease Rare disease affecting children and adults Usually presents with chronic bone pain most often the legs Affects internal organs in 50 lungs heart kidneys or retroperitoneum the area between the abdomen and the back. Erdheim-Chester disease is a rare non-Langerhans cell histiocytosis histologically characterized by multi-systemic proliferation of mature histiocytes in a background of inflammatory stroma. See also Lymph node topic Very rare 100 cases reported nonfamilial neoplastic xanthogranulomatous non-Langerhans cell systemic histiocytosis first identified by William Chester in 1930 Usually associated with disease of long bones Etiology not well understood Mean age 57 years range 25 - 76 years no gender preference Three. CD1a- langerin- S100 histiocytes showing emperipolesis Langerhans cell sarcoma.
1 Historical classification of histiocytoses in a table.
Please use the drop down menus below for board review style questions by chapter or subspecialty. They are not intended to be actual questions. Case 299 Neck lymph node biopsy Skin lesion biopsy. Jump to navigation Jump to search. Pathologists among the many other integral specialties have been an important role in the process of diagnosing Erdheim-Chester Disease. 1 Historical classification of histiocytoses in a table.