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Drug Induced Agranulocytosis Treatment. If you have an infection your healthcare provider will prescribe antibiotics and other medications to. Drugs most often associated with neutropenia or agranulocytosis include dipyrone diclofenac ticlopidine calcium dobesilate spironolactone antithyroid drugs eg propylthiouracil carbamazepine sulfamethoxazole- trimethoprim 3-lactam antibiotics clozapine levamisole and vancomycin. Agranulocytosis is a serious side effect of antithyroid drugs. Long-term remission of hyperthy-roidism can be achieved in about 50 of patients with Graves disease treated with ATDs 1.
Granulocyte colony-stimulating factor decreases. Arch Immunol Ther Exp Warsz 1996. High-risk drugs include antithyroid drugs clozapine ticlopidine sulfasalazine dipyrone trimethoprimsulfamethoxazole carbamazepine and probably rituximab. Nine patients with drug-induced agranulocytosis received recombinant human granulocyte colony-stimulating factor rhG-CSF to accelerate myeloid recovery because of life-threatening infections related to neutropenia. To ascertain the knowledge of patients and review the quality of information available on the internet. Arch Immunol Ther Exp Warsz 1996.
The application of granulocyte-macrophage and granulocyte colony stimulation factors GM-CSF and G-CSF has been progressively increased in the treatment of patients with agranulocytosis.
To ascertain the knowledge of patients and review the quality of information available on the internet. Morbidity and perhaps mortality of antithyroid drug-induced agranulocytosis. To demonstrate that drug-induced agranulocytosis can occur after a very prolonged period of low-dose treatment with antithyroid medications. Granulocyte colony-stimulating factor G-CSF. Under an Elsevier user license. All patients showed a quick recovery of their granulocyte counts.