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Calcium Sulfate Bone Graft Substitute. The benefits of synthetic grafts include availability sterility and reduced morbidity. Calcium sulfate belongs to synthetic ceramic group of bone graft substitutes having an. Calcium sulfate CS features a unique position among all regenerative bone graft substitutes. Calcium sulfate plaster of Paris has a long clinical history for use as a bone graft substitute in various skeletal sites.
Calcium sulfate belongs to synthetic ceramic group of bone graft substitutes having an. Calcium Sulfate as Bone Graft Substitute in the Treatment of Osseous Bone Defects A Prospective Study Abstract. Treatment of large osseous bone defects is challenging. However the results of many studies have yielded inconclusive results. Autograft bone has osteogenic potential because surviving bone cells and matrix proteins are present. One example of a commercially available hydroxyapatite-based bone graft substitute is Pro-Osteonfrom BiometOsteobiologics.
Calcium sulfate is a well-tolerated biodegradable osteoconductive bone graft substitute.
Synthetic porous substitutes share several advantages over allografts including unlimited supply easy sterilization and storage. Furthermore calcium sulfate substitutes occupy a unique position in the group of regenerative materials and are recognized as safe and bioactive implant materials. With more than 100 years of documented clinical success Dreesmann 1892 Thomas and Puleo 2008 it has a longer history of clinical use when compared to most currently available biomaterials. When direct current electrical stimulation was added a trend toward successful fusion was observed in a dose-dependent manner but no statistical significance could be demonstrated. Synthetic bone substitutes consist of hydroxyapatite tricalcium phosphate calcium sulfate or a combination of these minerals. The benefits of synthetic grafts include availability sterility and reduced morbidity.