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Calcineurin Inhibitor Pain Syndrome. Collini A De Bartolomeis C Barni R et al. Calcineurin-inhibitor-induced pain syndrome CIPS a rare complication seen in patients with organ transplants is associated with the use of calcineurin inhibitors CIs such as cyclosporine CSP and tacrolimus FK. Calcineurin inhibitor-induced pain syndrome after kidney transplantation-a rare but disabling condition. Leg bone pain syndrome in a kidney transplant patient treated with tacrolimus FK506.
1Department of Internal Medicine University Hospital Zurich Zurich Switzerland. Authors Ankur Varma 1. Breitenstein A1 Stumpe KD2 Gnannt R3 Fehr T4 Etter C4. 5 coined the term Calcineurininhibitor pain syndrome CIPS for this pain syndrome. Published by Elsevier Inc. Sie inaktivieren die Serin-Threonin-Phosphatase Calcineurin die für die Transkription von Zytokinen und somit für einen Teil der Immunantwort notwendig ist.
Calcineurin-inhibitor induced pain syndrome CIPS is a condition characterized by lower extremity pain in patients receiving tacrolimus or cyclosporine therapy following organ transplantation.
The most commonly implicated drugs are cyclosporine and tacrolimus. Calcineurininhibitoren sind Arzneistoffe mit immunsuppressiver Wirkung. 2 It has not yet been described in the literature with pimecrolimus. Through two cases we demonstrate key imaging findings in CIPS with bone scintigraphy and magnetic resonan. Calcineurin-inhibitor induced pain syndrome CIPS is a condition describing reversible lower extremity pain in patients following organ transplantation. Calcineurin-inhibitor induced pain syndrome after stem cell transplant.