10
Dec
Amiodarone Pulmonary Toxicity Mechanism. It is not known whether the lung problems caused by amiodarone are due to direct damage by the drug to the lungs tissues to an immune reaction to the drug or to some other mechanism. Several features of this adverse effect make it difficult to diagnosis and treat. Acute toxicity eg acute respiratory distress syndrome is rare but is associated with high mortality up to 50. APTamiodarone pulmonary toxicity A miodarone long used for various arrhythmias has been associated with a long list of side effects.
Acute toxicity eg acute respiratory distress syndrome is rare but is associated with high mortality up to 50. APTamiodarone pulmonary toxicity A miodarone long used for various arrhythmias has been associated with a long list of side effects. The case of a 63-year-old male with classic radiographic and histologic findings of APT is discussed. It is not known whether the lung problems caused by amiodarone are due to direct damage by the drug to the lungs tissues to an immune reaction to the drug or to some other mechanism. The onset of pulmonary toxicity may be either insidious or rapidly progressive. Amiodarone has been implicated in pulmonary toxicity even though there is no direct link because 1 no other cause could be found for the reactions that occurred.
And 5 specific therapy for other possible pulmonary.
Several features of this adverse effect make it difficult to diagnosis and treat. Amiodarone lung toxicity probably affects up to 5 of patients taking this drug. Howeverseveralcauseshavebeenproposedincludingdirect or indirect toxicity. Amiodarone- induced pulmonary toxicity AIPT is characterized in part by oedema phospholipidosis inammation and thickening of the alveolar septa intra-alveolar inammation and pul- monary brosis. E etiology of AIPT is unknown. The mechanism of amiodarone pulmonary toxicity is unknown and recommendations for the assessment and treatment of patients with this condition continue to evolve.